Japan SOD Research Organization

Information on action, impediments and elimination of reactive oxygen species has been summarized from Dr. Niwa’s book and other official reference materials such as publications, conferences and various newspapers.

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  • Diseases caused by reactive oxygen species (from research reports)

Diseases caused by reactive oxygen species (from research reports)

Many researchers including Dr. Yukie (Kozo) Niwa, Director of Tosashimizu Hospital (Kyoto University, Doctor of Medicine) and a pioneer researcher of reactive oxygen species and SOD, have published reports concerning “damage caused by reactive oxygen species” and “diseases caused by reactive oxygen species” in various publications and newspaper articles. Here are reports from four researchers.

According to Dr. Yukie (Kozo) Niwa
  • Vascular diseases: Prevention of aging of blood vessels, atherosclerosis, cerebral apoplexy, cerebral infarction, myocardial infarction, etc.
  • Internal diseases: Diabetes (cataract), hepatitis, nephritis, stomach ulcer, intestinal ulcer, etc.
  • Dermatological diseases: Atopic dermatitis, blemishes, freckles, wrinkles, dry skin, burns, etc.
  • Serious diseases: Cancer, articular rheumatism, collagen disease, Behcet’s disease, Kawasaki disease, etc.
  • Others: Neuralgia, poor circulation, fatigue, inflammation (hay fever and rhinitis are inflammatory disorders), etc.
According to Mr. Kunihiko Kato, Department of Science, University of Tokyo
  • Vascular diseases: Aging, atherosclerosis, cerebral apoplexy, myocardial infarction, etc.
  • Internal diseases: Diabetes (cataract), onset of cancer, spread of cancer, disorders in the gastric mucosa, etc.
  • Others: Rheumatism, epileptic seizures, etc.
According to Ms. Nobuko Minagawa, Lecturer, Niigata University of Pharmacy and Applied Life Sciences
  • Cardiological diseases: Atherosclerosis, ischemia-reperfusion injury
  • Respiratory diseases: Emphysema, adult respiratory distress syndrome, paraquat intoxication
  • Diseases of the cranial nerve: Cerebral edema, traumatic epilepsy, Parkinson’s disease, spinal injury
  • Digestive diseases: Disorders of the gastric mucosa, ulcerative colitis, Crohn’s disease, drug-induced hepatic injury, acute pancreatitis
  • Hematological diseases: Hemoglobinopathy, drug-induced anemia, disseminated intravascular coagulation
  • Endocrinological diseases: Diabetes
  • Urological diseases: Glomerulonephritis, drug-induced nephropathy
  • Skin diseases: Burns, skin inflammation from sunlight
  • Diseases of the supportive tissues: Collagen disease
  • Ophthalmological diseases: Cataract, retinopathy of prematurity
  • Tumors: Chemical onset of cancer and chemotherapy, radiation damage and radiotherapy
According to Mr. Yutaka Sakai, Professor Emiritus, National Defense Medical College
  • Vascular diseases: Aging, angina, myocardial infarction, etc.
  • Internal diseases: Diabetes (cataract), cancer, etc.
  • Others: Rheumatism, senile dementia, stress-induced disorders, etc.

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